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Wegovy injections for weight loss in Ireland

Wegovy (semaglutide) is a once-weekly injectable prescription medicine used for weight loss in adults who are overweight or have obesity, and to help manage blood sugar levels in adults with type 2 diabetes. In order to maximise benefits, Wegovy should be used alongside a plan for diet and exercise. Generally, treatment can be suitable for patients with a BMI of 30 or above, or a BMI of 27 or above if you have a weight-related health condition such as high blood pressure.

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Patient Information: Wegovy

What is Wegovy?

Wegovy is a prescription medicine containing the active substance semaglutide. It is prescribed for adults to support weight management and weight control, and is also used in the treatment of type 2 diabetes. It works by acting on receptors in the brain that control your appetite, which can make you feel fuller, less hungry, and experience fewer food cravings.

This medicine is designed to work alongside lifestyle modifications. To achieve the best results, it should be part of a plan that includes a reduced-calorie diet and increased physical activity. Your GP or specialist will prescribe this based on your specific health needs.

Key Information

  • Active Ingredient: Semaglutide
  • Administration: Once-weekly injection you can do yourself
  • Primary Uses: Treating type 2 diabetes and weight management
  • Availability: Pre-filled pen; subject to clinician assessment

Eligibility criteria for Wegovy in Ireland

BMI Thresholds for Eligibility

Eligibility is primarily determined by your Body Mass Index (BMI), which is a measure of your weight relative to your height:

BMI of 30kg/m² or higher: You are generally eligible for treatment based on your weight alone.

BMI of 27kg/m² to 29.9kg/m²: You can't usually access the medication based on weight alone in this range. You'll need to have at least one weight-related health condition, such as:

  • High blood pressure (hypertension)
  • High cholesterol
  • Obstructive sleep apnoea
  • Prediabetes or Type 2 diabetes
  • Heart disease

A doctor will check your health profile to ensure there are no medical reasons that prevent you from taking it. For example, generally, you won't be suitable for Wegovy if you have:

  • Specific Family History: A history of Medullary Thyroid Carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
  • Pancreatic or Digestive Issues: A history of severe pancreatitis or severe gastroparesis (where the stomach empties too slowly).
  • Pregnancy: If you are pregnant, planning to become pregnant, or breastfeeding.
  • Conflicting Medications: If you are already taking other GLP-1 medications or certain diabetes treatments.

Wegovy Dosing Titration

Wegovy dosage schedule showing 20-week progression from 0.25mg to 2.4mg

How much weight can I lose on Wegovy?

Clinical studies have shown patients can lose up to 17% of their weight by following a combination of weekly Wegovy injections over an extended period and consistent lifestyle changes.

Results

70 kg200 kg

With our personalised plan, you could reach 86 kg in 10 months. That's a weight loss of 14 kg.

Projected
Continued

This projection is based on the average results from large-scale clinical trials and is for informational purposes only.

Clinical trials have observed the following changes for some patients:

  • Average weight loss: 15% of body weight over 10 months in clinical trials
  • Cardiovascular benefits: May reduce risk of heart disease and stroke
  • Blood sugar control: Can improve insulin sensitivity and glucose regulation
  • Appetite regulation: Helps reduce food cravings and portion sizes
  • Long-term maintenance: Supports sustained weight management when combined with lifestyle changes

Note: Individual results vary. These outcomes are based on clinical trial data and should be discussed with your healthcare provider.

How to Administer Wegovy

Before first use, your healthcare provider should show you how to inject it. Always read the full "Instructions for Use" leaflet provided with your medicine.

  1. Prepare: check your pen contains your prescribed dose and the solution is clear and colourless. Always use a new needle for each injection.
  2. Choose your injection site: front of your upper legs, your stomach, or your upper arms.
  3. Rotate your site: you may inject in the same body area each week, but not the exact same spot.
  4. Inject: follow the leaflet to set your dose; press and hold the dose button until the counter shows 0, then slowly count to 6 before removing the needle.
  5. Dispose: unscrew the needle immediately after injection and dispose of it safely. Never store your pen with a needle attached.
Wegovy injection site locations showing recommended areas on upper arms, abdomen, and thighs

Important Note: Every time you inject, select a new location that is at least a finger's width apart from the previous site. Rotating your injection sites is crucial for preventing the development of persistent, hard lumps (fatty nodules), which can form and reduce how well your medication works.

The Potential Side Effects of Wegovy

Like all medicines, Wegovy can cause side effects, although not everybody will experience them. It's important to be aware of what to look for.

Common (may affect more than 1 in 10): headache, nausea, vomiting, diarrhoea, constipation, stomach pain, feeling weak or tired. These usually pass over time as your body adjusts.

Rare – seek immediate medical attention:

  • Signs of acute pancreatitis (severe, long-lasting stomach pain that may move to the back)
  • Severe allergic reactions (breathing problems, swelling of face/throat, wheezing, fast heartbeat)
  • Bowel obstruction (severe constipation with stomach ache, bloating, vomiting)
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